The UK medicines regulator has confirmed there is no evidence that taking paracetamol during pregnancy causes autism in children, and says pregnant women should continue to follow NHS guidance and take the medicine as directed.
In a statement published on Monday (22 September) and updated yesterday (Tuesday 23 September), the Medicines and Healthcare products Regulatory Agency (MHRA) said paracetamol remains the recommended pain-relief option in pregnancy when used at the lowest dose for the shortest time needed.
Dr Alison Cave, the MHRA’s Chief Safety Officer, said patient safety is the top priority and that advice is based on rigorous assessment of the best available evidence. She added that untreated pain and fever can pose risks to the unborn baby, so it is important to manage symptoms with recommended treatment and speak to a healthcare professional with any concerns.
The MHRA also encouraged the public and health professionals to report suspected side effects via the Yellow Card scheme.
Key points
- Paracetamol is still the first-choice painkiller in pregnancy when used as directed.
- There is no evidence it causes autism in children.
- Use the lowest effective dose for the shortest duration.
- Do not stop necessary pain or fever treatment without medical advice.
- Suspected side effects can be reported to the MHRA Yellow Card scheme.
Note: There has been recent misinformation circulating online about paracetamol and autism. This MHRA update directly addresses that and reaffirms existing NHS advice.